产品说明
一般描述
Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II, a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane. Many cancers are generally positive for SDHB, including renal cell carcinomas (RCC) and gastrointestinal stromal tumors (GIST). However, a subset of RCC and GIST tumors that are associated with SDH mutations, Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.
质量
 IVD |  IVD |  IVD |  RUO |
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
制备说明
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其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
产品性质
| 质量水平 | 500 100 |
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | culture supernatant |
| antibody product type | primary antibodies |
| 克隆 | EP288, monoclonal |
| 描述 | For In Vitro Diagnostic Use in Select Regions |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| 包装 | vial of 0.1 mL concentrate (466R-14) vial of 0.1 mL concentrate Research Use Only (466R-14-RUO) vial of 0.5 mL concentrate (466R-15) vial of 1.0 mL concentrate (466R-16) vial of 1.0 mL concentrate Research Use Only (466R-16-RUO) vial of 1.0 mL pre-dilute Research Use Only (466R-17-RUO) vial of 1.0 mL pre-dilute ready-to-use (466R-17) vial of 7.0 mL pre-dilute ready-to-use (466R-18) vial of 7.0 mL pre-dilute ready-to-use Research Use Only (466R-18-RUO) |
| manufacturer/tradename | Cell Marque™ |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated) |
| 同位素/亚型 | IgG |
| 控制 | GIST |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| 可视化 | cytoplasmic |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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