产品说明
一般描述
The claudin-family proteins are a group of tight-junction membranous proteins responsible for paracellular molecular flow between adjacent cells of the epithelium.1 In normal kidney, claudin-4 plays a key role in paracellular ion reabsorption.2 Claudin-4 is expressed in most epithelial cells yet is absent in mesothelial cells, making it of great use in characterizing epithelial malignincies.3 Immunohistochemical identification of this antigen may help identify poorly differentiated lung adenocarcinoma from lesions of mesothelial origin.4 Likewise, identification of claudin-4 expression by IHC may be useful in characterizing breast and endometrial lesions.5,6
质量
United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
制备说明
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其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
产品性质
| 质量水平 | 500 100 |
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | culture supernatant |
| antibody product type | primary antibodies |
| 克隆 | EP417, monoclonal |
| 描述 | For In Vitro Diagnostic Use in Select Regions |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| 包装 | vial of 0.1 mL concentrate (468R-14) vial of 0.1 mL concentrate Research Use Only (468R-14-RUO) vial of 0.5 mL concentrate (468R-15) vial of 1.0 mL concentrate (468R-16) vial of 1.0 mL concentrate Research Use Only (468R-16-RUO) vial of 1.0 mL pre-dilute Research Use Only (468R-17-RUO) vial of 1.0 mL pre-dilute ready-to-use (468R-17) vial of 7.0 mL pre-dilute ready-to-use (468R-18) vial of 7.0 mL pre-dilute ready-to-use Research Use Only (468R-18-RUO) |
| manufacturer/tradename | Cell Marque™ |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 (concentrated) |
| 同位素/亚型 | IgG |
| 控制 | lung adenocarcinoma |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| 可视化 | membranous |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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