产品说明
一般描述
Anti-cytokeratin cocktail (AE1 & AE3) is the broad-spectrum keratin antibody cocktail. It is composed of mouse monoclonal antibody AE1 that recognizes the acidic type I keratins 10, 14, 15, 16, 19, and AE3 that reacts with the basic type II keratins 1, 2, 3, 4, 5, 6, 7, and 8. Both clones were generated using epidermal keratin as immunogen.This antibody detects almost all carcinomas of different organ origin, but is most frequently negative in hepatocellular carcinoma, chromophobe RCC, adrenal corticol carcinoma, some clear cell renal cell carcinomas, and renal oncocytoma. This antibody cocktail can cross-react with other intermediate filaments, such as glial fibrillary acidic protein, giving a false-positive staining in glial tumors.
质量
IVD | IVD | IVD | RUO |
联系
Cytokeratin Cocktail Positive Control Slides, Product No. 313S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
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其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
基本信息
NACRES | NA.41 |
产品性质
质量水平 | 500 100 |
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | culture supernatant |
antibody product type | primary antibodies |
克隆 | AE1 & AE3, monoclonal |
描述 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
形式 | buffered aqueous solution |
species reactivity | human |
包装 | vial of 0.1 mL concentrate (313M-14) vial of 0.5 mL concentrate (313M-15) bottle of 1.0 mL predilute (313M-17) vial of 1.0 mL concentrate (313M-16) bottle of 7.0 mL predilute (313M-18) |
manufacturer/tradename | Cell Marque™ |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
同位素/亚型 | IgG1κ |
控制 | breast, colon, prostate, skin |
运输 | wet ice |
储存温度 | 2-8℃ |
可视化 | cytoplasmic |
Sigma-Aldrich