产品说明
一般描述
STAT6, a member of the signal transducers and activators of transcription (STAT) family, has been found to form recurrent fusions with NAB2 on chromosome 12q13 in the majority of solitary fibrous tumors. Inactivated STAT6 can be found in the form of a dimer located in the cytoplasm. STAT6 and NAB2 fusion enables cytosolic STAT6 to migrate to the nucleus and thus allowing for detection in immunohistochemical assays. NAB2-STAT6 fusion transcriptions have been reported in the majority of solitary fibrous tumors but not in meningiomas, hemangioblastomas, schwannomas, and hemangiomas. This makes STAT6 a useful marker in distinguishing solitary fibrous tumors from other morphologically similar tumors.
质量
 IVD |  IVD |  IVD |  RUO |
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
制备说明
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其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
产品性质
| 质量水平 | 500 100 |
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | culture supernatant |
| antibody product type | primary antibodies |
| 克隆 | EP325, monoclonal |
| 描述 | For In Vitro Diagnostic Use in Select Regions |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| 包装 | vial of 0.1 mL concentrate (426R-14) vial of 0.1 mL concentrate Research Use Only (426R-14-RUO) vial of 0.5 mL concentrate (426R-15) vial of 1.0 mL concentrate (426R-16) vial of 1.0 mL concentrate Research Use Only (426R-16-RUO) vial of 1.0 mL pre-dilute Research Use Only (426R-17-RUO) vial of 1.0 mL pre-dilute ready-to-use (426R-17) vial of 7.0 mL pre-dilute ready-to-use (426R-18) vial of 7.0 mL pre-dilute ready-to-use Research Use Only (426R-18-RUO) |
| manufacturer/tradename | Cell Marque™ |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated) |
| 同位素/亚型 | IgG |
| 控制 | solitary fibrous tumor |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| 可视化 | nuclear |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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