产品说明
一般描述
1-Bromopinacolone is an α-bromoketone-aldehyde. Coupling of 1-bromopinacolone with various aldehyde electrophiles catalyzed by SmI2 has been reported. It acts as reversible competitive inhibitor for acetylcholinesterase, during hydrolysis of acetylcholine.
应用
1-Bromopinacolone is the suitable reagent for the synthesis of a photolabile azido derivative of the kaurene oxidase inhibitor 1-(4- chlorophenyl)4,4-dimethyl-2-(1,2,4-triazol-1-yl) pentan-3-ol (paclobutrazol). It may be used as reagent in the synthesis of 2-t-butyl-6-benzoylimidazo[1,2-b]pyridazine.
包装
5, 25 mL in glass bottle
基本信息
| 线性分子式 | (CH3)3CCOCH2Br |
| 分子量 | 179.05 |
| Beilstein | 506485 |
| EC 号 | 226-794-0 |
| MDL编号 | MFCD00000206 |
| PubChem化学物质编号 | 24865895 |
| NACRES | NA.22 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥97% |
| 折射率 | n |
| bp | 188-194 ℃ (lit.) |
| mp | −10 ℃ (lit.) |
| 密度 | 1.331 g/mL at 25 ℃ (lit.) |
| 储存温度 | −20℃ |
| SMILES string | CC(C)(C)C(=O)CBr |
| InChI | 1S/C6H11BrO/c1-6(2,3)5(8)4-7/h4H2,1-3H3 |
| InChI key | SAIRZMWXVJEBMO-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | 167.0 °F - closed cup |
| 闪点(C) | 75 ℃ - closed cup |
| 个人防护装备 | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
Sigma-Aldrich
m.cnreagent.com
