产品说明
一般描述
Finding the right chemical that matches your pharma and biopharma manufacturing needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for pharma and biopharma manufacturing withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
应用
所有缓冲液的pH值都与温度和浓度有关。对于Tris缓冲液,降温每℃其pH值约增加0.03单位,每10倍稀释其pH降低0.03-0.05单位。
对于精确的应用,请使用带有玻璃/甘汞组合电极并仔细校准过的pH计。
其他说明
Due to its low microbial and endotoxin limits, Tris(hydroxymethyl)aminomethane hydrochloride Emprove® Expert is suitable for biopharma manufacturing needs.
法律信息
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
Trizma is a registered trademark of sigma-aldrich Co. LLC
基本信息
线性分子式 | NH2C(CH2OH)3 · HCl |
分子量 | 157.60 |
Beilstein | 3675235 |
MDL编号 | MFCD00012590 |
EC索引号 | 214-684-5 |
产品性质
质量水平 | 500 |
蒸汽压 | <1 Pa ( 50 ℃) |
产品线 | EMPROVE® EXPERT |
形式 | solid |
pH值(酸碱度) | 4.2 (20 ℃, 100 g/L in H2O) |
useful pH range | 7.0-9.0 |
pKa (25 ℃) | 8.1 |
mp | 150.7 ℃ |
溶解性 | soluble 561 g/L |
密度 | 1.28 g/cm3 at 20.2 ℃ |
储存温度 | 15-25℃ |
SMILES string | Cl.NC(CO)(CO)CO |
InChI | 1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H |
InChI key | QKNYBSVHEMOAJP-UHFFFAOYSA-N |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich