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Monoclonal Anti-CD40 antibody produced in mouse

品牌
Sigma-Aldrich
货号
WH0000958M1
规格纯度
clone 1G1, purified immunoglobulin, buffered aqueous solution
参考价格
4888.5 *本价格含增值税费
促销
服务
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数量
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产品名称:
Monoclonal Anti-CD40 antibody produced in mouse
Anti-p50
Anti-TNFRSF5
Anti-MGC9013
Anti-CD40 antigen (TNF receptor superfamily member 5)
Anti-CDW40
Anti-Bp50
产品介绍:

产品说明

一般描述

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. (provided by RefSeq)

免疫原

CD40 (AAH64518, 1 a.a. ~ 151 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MVRLPLQCVLWGCLLTAVHPEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHFHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIDICQPHFPKDRGLNLLM

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00282185
NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆1G1, monoclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型IgG2bκ
GenBank® accession no.BC064518
UniProt登记号P25942
运输dry ice
储存温度−20℃
Gene Informationhuman ... CD40(958)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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