Monoclonal Anti-ID3 antibody produced in mouse

产品说明

一般描述

The inhibitor of DNA-binding/differentiation 3 (Id3) protein is a helix-loop-helix transcription factor. This gene is located on human chromosome 1p36.
Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.[supplied by OMIM]

免疫原

ID3 (NP_002158, 1 a.a. ~ 83 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVV

生化/生理作用

The inhibitor of DNA-binding/differentiation 3 (Id3) is expected to play a major role in cell proliferation and differentiation. Overexpression of Id3 stimulates apoptosis in A549/DDP human lung cancer cells in vitro.

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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