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Monoclonal Anti-SLK antibody produced in mouse

品牌
Sigma-Aldrich
货号
WH0009748M1
规格纯度
clone 3E9, purified immunoglobulin, buffered aqueous solution
参考价格
6082.18 *本价格含增值税费
促销
服务
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数量
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产品名称:
Monoclonal Anti-SLK antibody produced in mouse
Anti-bA16H23.1
Anti-STK2
Anti-KIAA0204
Anti-STE20-like kinase (yeast)
Anti-se209
产品介绍:

产品说明

一般描述

STE20 like kinase (SLK) is a 1204 amino acid serine/threonine kinase. It possesses a kinase domain located at the amino-terminal and a C-terminal regulatory domain with coiled-coils. SLK is group V germinal center kinase that is expressed in the nucleus, cytosol, microtubules and centrosomes. The SLK gene is localized on human chromosome 10q24.33.

免疫原

SLK (NP_055535, 1126 a.a. ~ 1235 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSTQSRISKFYPIPSLHSTGS

生化/生理作用

STE20 like kinase (SLK) is a modulator of cell motility. It phosphorylates cytoskeleton-bound proteins, which take part in the remodeling of migratory cell architecture. SLK is also involved in mitogen-activated protein kinase pathways. It acts as an activator of Jun N-terminal kinase (JNK) and transactivates tumor suppressor p53.

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

基本信息

NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆3E9, monoclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型IgG1κ
GenBank® accession no.NM_014720
UniProt登记号Q9H2G2
运输dry ice
储存温度−20℃
Gene Informationhuman ... SLK(9748)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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