产品说明
一般描述
Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
应用
Benzalkonium chloride is typically used as a preservative in liquid formulations, e.g. for topical, ophthalmic, nasal and parenteral applications. It is effective against a wide range of bacteria, yeast and fungi.
Due to a defined C12:C14 ratio with high batch-to-batch consistency, Benzalkonium chloride Emprove® Expert provides higher solubility and antimicrobial activity. It can be used in combination with thimerosal, disodium edetate and benzyl alcohol to further increase antimicrobial activity.
This product is also available as 50% aqueous solution (Art.No. 137124).
法律信息
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 线性分子式 | C6H5CH2N(CH3)2RCl (R=C8H17 to C18H37) |
| Beilstein | 4062599 |
| UBA编号 | 12352200 |
| MDL编号 | MFCD00145757 |
| PubChem化学物质编号 | 24847423 |
产品性质
| 质量水平 | 500 |
| agency | NF Ph. Eur. |
| 产品线 | EMPROVE® EXPERT |
| 形式 | viscous liquid |
| 包装 | pkg of 1 kg |
| application(s) | liquid formulation ophthalmics parenterals pharmaceutical semi-solid formulation |
| 储存温度 | 15-25℃ |
| SMILES string | [Cl-].CCCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1 |
| InChI | 1S/C19H34N.ClH/c1-4-5-6-7-8-9-10-14-17-20(2,3)18-19-15-12-11-13-16-19;/h11-13,15-16H,4-10,14,17-18H2,1-3H3;1H/q+1;/p-1 |
| InChI key | TTZLKXKJIMOHHG-UHFFFAOYSA-M |
安全信息
| 象形图 |    |
| 警示用语： | Danger |
| 危险声明 | H302 + H312 - H314 - H410 |
| 预防措施声明 | P260 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338 |
| 危险分类 | Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B |
| 储存分类代码 | 8A - Combustible, corrosive hazardous materials |
| WGK | WGK 2 |
Sigma-Aldrich
m.cnreagent.com
