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Hsp25 Kinase Inhibitor-Calbiochem

品牌
Sigma-Aldrich
货号
385880
规格纯度
The Hsp25 Kinase Inhibitor controls the biological activity of Hsp25 KInase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
参考价格
2340.22 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Hsp25 Kinase Inhibitor-Calbiochem
MK2 Inhibitor, KKKALNRQLGVAA, MAPKAP Kinase-2 Inhibitor
KKKALNRQLGVAA, MK2 Inhibitor, MAPKAP Kinase-2 Inhibitor
产品介绍:

产品说明

一般描述

A 13-residue, cell-permeable peptide that acts as a potent and selective inhibitor of mammalian heat-shock protein (Hsp25) kinase. Inhibits Hsp25 kinase competitively with respect to the substrate peptide (Ki = 8.1 µM) and non-competitive with respect to ATP (Ki = 134 µM). [Hsp 25 kinase is also called mitogen-activated protein kinase-activated protein kinase-2 (MK2).]
A 13-residue, cell-permeable peptide that acts as a potent and selective inhibitor of mammalian heat-shock protein (Hsp25) kinase [also called mitogen-activated protein kinase-activated protein kinase-2 (MAPKAP kinase-2)]. Inhibition is competitive with respect to the substrate peptide (Ki = 8.1 µM) and non-competitive with respect to ATP (Ki = 134 µM).

包装

1 mg in Plastic ampoule

生化/生理作用

Target Ki: 8.1 µM against (Hsp25) kinase
Product does not compete with ATP.
Cell permeable: yes
Primary Target
(Hsp25) kinase
Reversible: no

警告

Toxicity: Standard Handling (A)

序列

H-Lys-Lys-Lys-Ala-Leu-Asn-Arg-Gln-Leu-Gly-Val-Ala-Ala-OH

外形

Supplied as a trifluoroacetate salt.

重悬

Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for up to months at -20°C.

其他说明

Katsoulidis, E., et al. 2005. Cancer Res.65, 9029.
Hayess, K., and Benndorf, R. 1997. Biochem. Pharmacol. 53, 1239.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C61H113N21O16
分子量1396.68

产品性质

质量水平100
测定≥98% (HPLC)
形式lyophilized solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
desiccated (hygroscopic)
颜色 white
溶解性DMSO: soluble
water: soluble
运输ambient
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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