产品说明
一般描述
A neutral glycosphingolipid (GSL) which is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco- series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase and c-fos expression in human aortic smooth muscle cells.
Molecular weight: 960.4 (based on tricosanyl -23:0)
A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase, and c-fos expression in human aortic smooth muscle cells.
M.W. 960.4 (based on tricosanoyl - 23:0).
包装
1 mg in Plastic ampoule
生化/生理作用
Product does not compete with ATP.
Reversible: no
Primary Target
A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL
Cell permeable: no
警告
Toxicity: Irritant (B)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
其他说明
Bhunia, A.K., et al. 1997. J. Biol. Chem.272, 15642.
Bhunia, A.K., et al. 1996. J. Biol. Chem.271, 10660.
Zacharias, C., et al. 1994. J. Biol. Chem.269, 13313.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C53H101NO13 |
| 分子量 | 960.37 |
| MDL编号 | MFCD00133445 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (TLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze |
| 颜色 | colorless |
| 溶解性 | ethanol: 1 mM methanol: 1 mM |
| 运输 | ambient |
| 储存温度 | −20℃ |
| InChI | 1S/C48H91NO13/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(53)49-36(37(52)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2)35-59-47-45(58)43(56)46(39(34-51)61-47)62-48-44(57)42(55)41(54)38(33-50)60-48/h29,31,36-39,41-48,50-52,54-58H,3-28,30,32-35H2,1-2H3,(H,49,53)/b31-29+/t36?,37?,38-,39-,41+,42+,43-,44-,45-,46+,47-,48?/m1/s1 |
| InChI key | VOZHMDQUIRUFQW-AIRKALMMSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
