产品说明
一般描述
Involved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC50 = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.
包装
1 mg in Plastic ampoule
生化/生理作用
Target IC50: 25-50 µM inhibiting MAP kinase in rat mesangial cells
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Involved in vasodilator actions of kinins such as bradykinin
警告
Toxicity: Harmful (C)
其他说明
Li, X., et al. 1995. Am. J. Physiol.269, C986.
Kessler, W., et al. 1992. Exp. Brain Res.91, 467.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C20H32O5 |
| 分子量 | 352.47 |
| MDL编号 | MFCD00077861 |
产品性质
| 质量水平 | 100 |
| 测定 | >98% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze |
| 颜色 | white to light yellow |
| 溶解性 | acetone: soluble ethanol: soluble ethyl acetate: soluble methanol: soluble |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| InChI | 1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4+,13-12+ |
| InChI key | XEYBRNLFEZDVAW-RTYMFESYSA-N |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H302 - H360FD |
| 预防措施声明 | P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313 |
| 危险分类 | Acute Tox. 4 Oral - Repr. 1B |
| 储存分类代码 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
Sigma-Aldrich
m.cnreagent.com
