产品说明
一般描述
A pyrrolocarbazole compound that acts as a potent, ATP-binding site-targeting inhibitor of Wee1 (IC50 = 11 nM) in an ATP-competitive manner and displays ~40-fold selectivity over the related checkpoint kinase Chk1 (IC50 = 440 nM).
A pyrrolocarbazole compound that acts as a poten, ATP-binding site-targeting inhibitor of Wee1 (IC50 = 11 nM) in an ATP-competitive manner and displays ~40-fold selectivity over the related checkpoint kinase Chk1 (IC50 = 440 nM).
包装
1 mg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Reversible: no
Product competes with ATP.
Cell permeable: no
警告
Toxicity: Standard Handling (A)
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C20H11ClN2O3 |
| 分子量 | 362.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥97% (HPLC) |
| 形式 | solid |
| 效能 | 11 nM IC50 |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze protect from light |
| 颜色 | light orange |
| 溶解性 | DMSO: 10 mg/mL ethanol: 10 mg/mL |
| 运输 | ambient |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
