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位置:首页 > 品牌 > Sigma-Aldrich > 异硫氰酸荧光素-葡聚糖

Fluorescein isothiocyanate–dextran

异硫氰酸荧光素-葡聚糖

品牌
Sigma-Aldrich
CAS
60842-46-8
货号
FD250S
规格纯度
average mol wt 250,000
参考价格
1903.01 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
60842-46-8
Fluorescein isothiocyanate–dextran
FITC–Dextran
异硫氰酸荧光素-葡聚糖
FITC-右旋糖酐
产品介绍:

产品说明

一般描述

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran. Conflicting data on the branch lengths implies that the average branch length is less than three glucose units. However, other methods indicate branches of greater than 50 glucose units exist. Native dextran has been found to have a molecular weight (MW) in the range of 9 million to 500 million. Lower MW dextrans will exhibit slightly less branching and have a more narrow range of MW distribution. Dextrans with MW greater than 10,000 behave as if they are highly branched. As the MW increases, dextran molecules attain greater symmetry. Dextrans with MW of 2,000 to 10,000, exhibit the properties of an expandable coil. At MW below 2,000, dextran is more rod-like. The MW of dextran is measured by one or more of the following methods: low angle laser light scattering, size exclusion chromatography, copper-complexation and anthrone reagent colorometric reducing-end sugar determination and viscosity.

应用

FITC-dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination. Small FITC-dextrans are also used to measure processes such as endocytosis. FITC-Dextran 250 (FD 250) may be used as a model compound for development of methods to deliver molecules into protoplasts and to study drug release from structures such as hydrogels and liposomes. It may be used as a model compound to study microvasculature and blood brain barrier.
FITC-dextran is used extensively in microcirculation and cell permeability research utilizing microfluorimetry. FITC-dextran has been used to study plant cell wall porosity and capillary permeability. Plasma proteins have been shown not to bind to FITC-dextran.
用异硫氰酸荧光素标记的葡聚糖可用于动物的灌注研究。

包装

100, 250 mg in poly bottle
1 g in poly bottle

制备说明

Sigma typically tests the solubility of FITC dextrans in water at concentrations at or above 25 mg/ml. Solutions should be protected from light. In vivo, FITC-dextran is stable for more than 24 hours.

基本信息

MDL编号MFCD00131092

产品性质

质量水平200
生物来源bacterial (Leuconostoc mesenteroides)
偶联物FITC conjugate
形式powder
分子量average mol wt 250,000
标记范围0.003-0.020 mol FITC per mol glucose
储存温度2-8℃

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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