产品说明
一般描述
Potent, reversible granzyme B and caspase-8 inhibitor.
A potent, reversible inhibitor of granzyme B and caspase-8 (Ki = 1 nM). Also inhibits caspase-1 (<6 nM), caspase-6 (5.6 nM), and caspase-10 (27 nM).
包装
1 mg in Plastic ampoule
生化/生理作用
Product does not compete with ATP.
Target Ki: 1 nM against caspase-8
Cell permeable: no
Reversible: yes
警告
Toxicity: Standard Handling (A)
序列
Ac-Ile-Glu-Thr-Asp-CHO
其他说明
Gao, C.F., et al. 2001. Exp. Cell. Res.265, 145.
Garcia-Calvo, M., et al. 1998. J. Biol. Chem.273, 32608.
Han, Z., et al. 1997. J. Biol. Chem. 272, 13422.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C21H34N4O10 |
| 分子量 | 502.52 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | lyophilized solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze |
| 颜色 | white |
| 溶解性 | DMSO: 1 mg/mL |
| 运输 | ambient |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
