产品说明
应用
Hck is a protein-tyrosine kinase that is expressed in hemopoietic cells. It is used in leukemia research .
生化/生理作用
Hck is a member of the Src tyrosine kinase family. Hck has been shown to associate with and be activated by Bcr-Abl, which is a protein-tyrosine kinase that is expressed in chronic myelogenous leukemia .
单位定义
One unit will phosphorylate 1.0 picomole of Tyr15 of the peptide substrate pcdc2 6-20 per minute at 30 ℃ at pH 7.4.
外形
Supplied as a solution in 50 mM Tris HCl, pH 7.4, 1 mM EDTA and 1 mM DTT
基本信息
| MDL编号 | MFCD03792313 |
| NACRES | NA.54 |
产品性质
| 质量水平 | 200 |
| 重组 | expressed in E. coli BL21 |
| 形式 | solution |
| specific activity | 1-2 unit/μg protein |
| 包装 | vial of ≥200 units |
| 相关疾病 | cancer (leukemia) |
| 运输 | dry ice |
| 储存温度 | −70℃ |
Sigma-Aldrich
m.cnreagent.com
