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Poly(lactide-alt-glycolide)

品牌
Sigma-Aldrich
货号
922692
规格纯度
average Mn 20,000, 50:50 (lactide:glycolide)
参考价格
3284.71 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Poly(lactide-alt-glycolide)
产品介绍:

产品说明

应用

Different from common Poly(lactide-co-glycolide) (PLGA) polymer, the lactic and glycolic units in Poly(lactide-alt-glycolide) alternate in sequence in the polymer chain, and the molar ratio of lactic to glycolic units in the polymer is exactly 1:1. Poly(lactide-alt-glycolide) exhibits excellent solubility in common organic solvents, such as acetonitrile, acetone, dioxane, DCM, and THF, providing great convenience for drug delivery researches and applications.
Common Poly(lactide-co-glycolide) (PLGA) is a biocompatible and biodegradable polymer that has been approved by the FDA for biomedical and pharmaceutical applications. PLGA based polymers are usually synthesized from copolymerization of glycolide (GA) and lactide (LA). However, the copolymerization of glycolide (GA) and Lactide (LA) typically results in broad composition ranges and a random block nature because of the much higher reactivity of GA and the drastic polymerization conditions. Thus, simple use of equimolar charges of GA and LA results in polymers containing longer glycolic blocks leads to poor solubility in common solvents.

基本信息

线性分子式(C5H6O4)n

产品性质

形式powder
质量水平100
投料比 50:50 (lactide:glycolide)
分子量average Mn 20,000
颜色 white to beige
储存温度2-8℃

Sigma-Aldrich

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