产品说明
一般描述
PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs.
应用
Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.
包装
1 g in glass bottle
特点和优势
Biocompatible, degradable, thermosensitive, high stability, small size (<200 nm) and properties can be easily modified.
基本信息
| NACRES | NA.23 |
产品性质
| 描述 | typical PEG PDI<1.1; overall PDI≤2.0 (THF, PS) |
| 质量水平 | 100 |
| 投料比 | lactide:glycolide 75:25 |
| 分子量 | PEG average Mn 1,000 PLGA average Mn 2,200 average Mn (1100-1000-1100) |
| 降解时间线 | 2-3 weeks |
| 转变温度 | Tm 230-235 ℃ |
| PDI | <2.0 |
| 储存温度 | 2-8℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
