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Anti-Interleukin-2 antibody produced in goat

品牌
Sigma-Aldrich
货号
I8273
规格纯度
IgG fraction of antiserum, lyophilized powder
参考价格
4731.57 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Interleukin-2 antibody produced in goat
Anti-IL-2
产品介绍:

产品说明

一般描述

Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4+ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signalling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signalling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle
Monoclonal Anti-Interleukin-2 recognizes human Interleukin-2. It also neutralizes recombinant, mouse IL-2, but requires 30-50 times the antibody concentration required to neutralize human IL-2.

特异性

The antibody neutralizes the biological activity of recombinant human IL-2.

免疫原

recombinant human interleukin-2 expressed in Escherichia coli.

应用

Anti-interleukin-2 antibody is suitable for IL-2 neutralization assays.

外形

Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline containing carbohydrates.

制备说明

Purified using protein G.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00675261

产品性质

质量水平100
生物来源goat
偶联物unconjugated
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式lyophilized powder
species reactivityhuman
technique(s)neutralization: suitable
western blot: 1 μg/mL
UniProt登记号P60568
储存温度−20℃
Gene Informationhuman ... IL2(3558)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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