产品说明
一般描述
The antibody neutralizes the biological activity of recombinant human IL-5.
免疫原
recombinant human IL expressed in Sf 21 insect cell line.
生化/生理作用
Interleukin-5 is a T-cell derived cytokine that induces the differentiation of B cells into antibody producing plasma cells. It is a critical differentiation factor for eosinophils and regulates the expression of genes required for cell proliferation, survival and maturation. The cellular functions of IL-5 are mediated by JAK-STAT, Btk and Ras/Raf-ERK signaling pathways. IL-5 is a good molecular target for the treatment of eosinophilic diseases.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
制备说明
Purified using protein G.
基本信息
| MDL编号 | MFCD00212216 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | goat |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | lyophilized powder |
| species reactivity | human |
| technique(s) | indirect ELISA: 0.5-1.0 μg/test neutralization: suitable western blot: 1-2 μg/mL |
| UniProt登记号 | P05113 |
| 储存温度 | −20℃ |
| Gene Information | human ... IL5(3567) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
