Anti-Matrix Metalloproteinase-7, N-Terminal of Catalytic Zinc Site antibody produced in rabbit

产品说明

一般描述

Matrix metallopeptidase 7 (MMP-7) is also known as matrilysin and expressed in tumor cells. It possesses many α-helices and β-sheets, with an active domain. The gene is localized on human chromosome 11q21-q22.

特异性

Reacts with reduced and non-reduced MMP-7.

免疫原

synthetic peptide corresponding to the N-terminal end of the catalytic zinc site of human matrix metalloproteinase-7 (matrilysin, PUMP).

应用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Anti-matrix metalloproteinase-7, N-terminal of catalytic zinc site antibody produced in rabbit has been used in immunohistochemistry and Western blotting.

生化/生理作用

Matrix metallopeptidase 7 (MMP-7) is a proteolytic enzyme which acts on fibronectin, laminin and collagen type IV. It can also activate other metalloproteinases like MMP-2 and MMP-9. MMP-7 plays an important role in the growth of cancerous cells.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

产品性质