产品说明
一般描述
RB1 (RB transcriptional corepressor 1) codes for nuclear phosphoprotein pRB (retinoblastoma protein). It is located on chromosome 13q14. It is a tumor-suppressor gene.
免疫原
synthetic phosphopeptide derived from the region of human Rb that contains Ser807.
生化/生理作用
RB1 (RB transcriptional corepressor 1) plays an important role throughout G1/S phase transition. Absence of RB induces prostate cancer metastasis. It plays an important role in modulating the cell cycle. It also regulates cell stemness and differentiation.
外形
Solution in phosphate buffer, pH 7.4, containing 1 mg/mL BSA (protease and IgG-free) and 0.05% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD06411895 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | western blot: 0.25-0.75 μg/mL using Jurkat cells in high growth phase. |
| UniProt登记号 | P06400 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... RB1(5925) |
Sigma-Aldrich
m.cnreagent.com
