产品说明
一般描述
A potent and irreversible inhibitor of caspase-9 (ICE-LAP6, Mch6). Reported to reduce myocardial infarct size during reperfusion (~70 nM).
A potent, irreversible inhibitor of caspase-9. Reported to reduce myocardial infarct size during reperfusion (~70 nM).
包装
1 mg in Plastic ampoule
生化/生理作用
Cell permeable: yes
Target IC50: 70 nM against caspase-9
Primary Target
caspase-9
Product does not compete with ATP.
Reversible: no
警告
Toxicity: Standard Handling (A)
序列
Ac-Leu-Glu-His-Asp-CMK
其他说明
Mocanu, M.M., et al. 2000. Br. J. Pharmacol.130, 197.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C24H35ClN6O9 |
分子量 | 587.02 |
产品性质
质量水平 | 100 |
测定 | ≥95% (HPLC) |
形式 | solid |
manufacturer/tradename | Calbiochem® |
储存条件 | OK to freeze desiccated |
颜色 | white |
溶解性 | water: 1 mg/mL DMSO: 5 mg/mL |
运输 | ambient |
储存温度 | −20℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich