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Monoclonal Anti-m/μ Calpain, Small Subunit antibody produced in mouse

品牌
Sigma-Aldrich
货号
C0230
规格纯度
~1 mg/mL, clone 28F3, purified immunoglobulin, buffered aqueous glycerol solution
参考价格
4731.57 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Monoclonal Anti-m/μ Calpain, Small Subunit antibody produced in mouse
产品介绍:

产品说明

一般描述

Calpain small subunit 1 (Capns1) is a small regulatory subunit associated with the μ-calpain (calpain 1) and m-calpain (calpain 2). The CAPNS1 gene is mapped to human chromosome 19q13.12.

免疫原

purified calpain from human placenta.

应用

Monoclonal Anti-m/μ Calpain, Small Subunit antibody produced in mouse has been used in immunoprecipitation and immunoblotting.

生化/生理作用

Calpain small subunit 1 (Capns1) participates in the actin cytoskeleton rearrangement and cell migration events. It is crucial for embryonic development. Capns1 interacts with the Ras GTPase activating protein Src homology 3 domain (SH3) (RasGAP-SH3) domain to regulate cell migration and cell survival. It is essential for calpain activity. Capns1 is associated with the oncogenesis of many tumor types including hepatocellular, colorectal, ovarian, and breast cancer.

外形

Solution in 0.02 M sodium phosphate, pH 7.5, and 0.15 M sodium chloride containing 50% glycerol and 3 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD01864149
NACRESNA.41

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆28F3, monoclonal
形式buffered aqueous glycerol solution
分子量antigen 28-30 kDa
species reactivityhuman, bovine
浓度~1 mg/mL
technique(s)immunoprecipitation (IP): suitable
western blot: 1:5,000 using normal human fibroblasts or MDBK cells
同位素/亚型IgG1
UniProt登记号Q96L46
运输wet ice
储存温度−20℃
Gene Informationhuman ... CAPNS1(826), CAPNS2(84290)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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