Chaetoglobosin A

产品名称：

50335-03-0
Chaetoglobosin A
4,7,14,14a,15,15a,16a,16b-Octahydro-7-hydroxy-14-(1H-indol-3-ylmethyl)-4,6,15,15a-tetramethyl-
3H-Cyclotridec[d]oxireno[f]isoindole-8,11,12(13H)-trione

产品介绍：

产品说明

应用

Chaetoglobosin A has been used as a standard for the detection and quantification of chaetoglobosin A from Chaetomium globosum by HPLC.

生化/生理作用

Chaetomium globosum is a fungus commonly found in water-damaged walls and causes Sick Building Syndrome (SBS).Chaetoglobosin A is a mycotoxic cytochalasin. Over 40 chaetoglobosins were characterized, many of which show acute toxicity to mammals, as well as cytotoxicity to human cancer cell lines such as KB, K562, MCF-7, and HepG2.
Cytochalasins were also found to inhibit glucose transport in human erythrocytes by binding to the glucose carrier on the erythrocyte membrane.Chaetoglobosin A was found to inhibit nematode proliferation and egg hatching. It also causes mortality of second stage juveniles of Meloidogyne incognita.

其他说明

Store the product sealed at −20 ℃. Under these conditions the product is stable for at least 2 years.

基本信息

经验(实验)分子式	C₃₂H₃₆N₂O₅
分子量	528.64
NACRES	NA.77

产品性质

质量水平	200
生物来源	Chaetomium globosum
测定	≥98% (HPLC)
溶解性	DMSO: soluble 10 mg/mL methanol: soluble 10 mg/mL
储存温度	−20℃
InChI	1S/C32H36N2O5/c1-17-8-7-10-22-29-31(4,39-29)19(3)27-24(15-20-16-33-23-11-6-5-9-21(20)23)34-30(38)32(22,27)26(36)13-12-25(35)28(37)18(2)14-17/h5-7,9-14,16-17,19,22,24,27-29,33,37H,8,15H2,1-4H3,(H,34,38)/b10-7+,13-12+,18-14+/t17-,19-,22?,24-,27-,28+,29-,31+,32+/m0/s1
InChI key	OUMWCYMRLMEZJH-VIRVUJSBSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable