产品说明
应用
Complement factor H (CFH) is a plasma regulator of the complement protein C3b in the alternative pathway of the complement system. Research has shown that binding of CFH is important for pathogenesis of group A streptococcus (GAS), and inhibition of this binding may be an effective management of GAS infections.
生化/生理作用
Complement factor H plays an essential role in the homeostasis of the complement system and in preventing collateral damage to bystander cells and tissues by complement activation.
C3b-binding protein which regulates the formation and function of complement C3 and C5 convertases.
其他说明
View more information on the complement pathway at www.sigma-aldrich.com/enzymeexplorer
基本信息
| MDL编号 | MFCD00166551 |
| NACRES | NA.61 |
产品性质
| 质量水平 | 200 |
| 生物来源 | human plasma |
| 测定 | ≥90% (SDS-PAGE) |
| 形式 | liquid |
| 浓度 | 1 mg/mL in PBS, pH 7.2 |
| technique(s) | activity assay: suitable |
| UniProt登记号 | P08603 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... CFH(3075) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
