您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > MMP Inhibitor II-CAS 203915-59-7-Calbiochem

MMP Inhibitor II-CAS 203915-59-7-Calbiochem

品牌
Sigma-Aldrich
CAS
203915-59-7
货号
444247
规格纯度
The MMP Inhibitor II, also referenced under CAS 203915-59-7, controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
参考价格
2462.32 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
203915-59-7
MMP Inhibitor II-CAS 203915-59-7-Calbiochem
N-Hydroxy-1,3-di-(4-methoxybenzenesulphonyl)-5,5-dimethyl-[1,3]-piperazine-2-carboxamide
产品介绍:

产品说明

一般描述

A potent, reversible, broad-range inhibitor of matrix metalloproteinases. Inhibits MMP-1 (IC50 = 24 nM), MMP-3 (IC50 = 18.4 nM), MMP-7 (IC50 = 30 nM), and MMP-9 (IC50 = 2.7 nM).
A potent, reversible, broad range inhibitor of matrix metalloproteinases. Inhibits MMP-1 (IC50 = 24 nM), MMP-3 (IC50 = 18.4 nM), MMP-7 (IC50 = 30 nM), and MMP-9 (IC50 = 2.7 nM).

包装

1 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Cell permeable: yes
Product does not compete with ATP.
Reversible: yes
Target IC50: 24 nM, 18.4 nM, 30 nM, 2.7 nM, against MMP-1, MMP-3, MMp-7, and MMP-9, respectively

警告

Toxicity: Standard Handling (A)

制备说明

Requires vigorous vortexing for 60 seconds to completely solubilize the product.

其他说明

Pikul, S., et al. 1998. J. Med. Chem. 41, 3568.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C21H27N3O8S2
分子量513.58

产品性质

质量水平100
测定≥95% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
颜色 off-white
溶解性DMSO: 100 mg/mL
运输ambient
储存温度−20℃
InChI1S/C21H27N3O8S2/c1-21(2)13-23(33(27,28)17-9-5-15(31-3)6-10-17)20(19(25)22-26)24(14-21)34(29,30)18-11-7-16(32-4)8-12-18/h5-12,20,26H,13-14H2,1-4H3,(H,22,25)
InChI keyMCSWSPNUKWMZHM-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品