(1S,2R,8R,8aR)-1,2,8-八氢吲哚啶三醇

产品名称：

72741-87-8
Swainsonine
(1S,2R,8R,8aR)-1,2,8-Octahydroindolizidinetriol
苦马豆素
(1S,2R,8R,8aR)-1,2,8-八氢吲哚啶三醇

产品介绍：

产品说明

应用

Swainsonine is an indolizidine alkaloid from the plant Metarrhizium anisopliae that is used as a potent α-mannosidase inhibitor. Product S8195 has been used in chemical inhibition assays of CHO Lec2 cells to inhibit glycosylation .
苦马豆素是各种α-甘露糖苷酶的有效抑制剂，特别是α-甘露糖苷酶II。它能够抑制糖蛋白加工，也可作为免疫调节剂。

生化/生理作用

Swainsonine is a potent α-mannosidase inhibitor. It also has antimetastatic, antiproliferative, and immunomodulatory activity . It also inhibits glycoprotein processing.

包装

1MG

制备说明

Soluble in water, methanol, DMSO

其他说明

Keep container tightly closed in a dry and well-ventilated place.

基本信息

经验(实验)分子式	C₈H₁₅NO₃
分子量	173.21
Beilstein	4175740
MDL编号	MFCD00017554
PubChem化学物质编号	24899779
NACRES	NA.85

产品性质

质量水平	200
生物来源	Metarrhizium anisopliae
测定	≥98% (TLC)
形式	lyophilized powder
储存条件	(Keep container tightly closed in a dry and well-ventilated place.)
颜色	white to faint yellow
溶解性	H₂O: soluble 1 mg/mL
作用机制	enzyme \| inhibits
抗生素抗菌谱	neoplastics
储存温度	2-8℃
SMILES string	O[C@@H]1CCCN2C[C@@H](O)[C@@H](O)C12
InChI	1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7?,8-/m1/s1
InChI key	FXUAIOOAOAVCGD-DCDLSZRSSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves