产品说明
一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Cholecalciferol, also referred to as vitamin D3, promotes the absorption of calcium and phosphorus in the body to regulate bone growth. It is most commonly found in humans and animals and is produced in our skin when exposed to sunlight. It is used to treat and prevent bone disorders (such as rickets, osteomalacia).
应用
Cholecalciferol for system suitability may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.
生化/生理作用
维生素 D 借以发挥作用的受体是配体依赖性转录因子超家族的成员。调控正常细胞和癌细胞的增殖和分化。对乳腺癌、结肠癌和前列腺癌细胞具有抗增殖和抗转移作用。肠和骨骼中的活化维生素 D 受体维持着钙的吸收和平衡。
包装
Unit quantity: 1 mL. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
注意
Please find SDS provided by EDQM here..
其他说明
Sales restrictions may apply.
基本信息
| 经验(实验)分子式 | C27H44O |
| 分子量 | 384.64 |
| Beilstein | 2339331 |
| MDL编号 | MFCD00078131 |
| PubChem化学物质编号 | 329774967 |
| NACRES | NA.24 |
产品性质
| 生物来源 | synthetic |
| 等级 | pharmaceutical primary standard |
| agency | EP |
| 形式 | solid |
| manufacturer/tradename | EDQM |
| technique(s) | gas chromatography (GC): suitable liquid chromatography (LC): suitable |
| mp | 83-86 ℃ (lit.) |
| application(s) | pharmaceutical (small molecule) |
| 格式 | neat |
| 储存温度 | −20℃ |
| SMILES string | CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C |
| InChI | 1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1 |
| InChI key | QYSXJUFSXHHAJI-YRZJJWOYSA-N |
| Gene Information | human ... VDR(7421) |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H300 + H310 + H330 - H372 |
| 预防措施声明 | P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314 |
| 危险分类 | Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 1 Oral |
| 储存分类代码 | 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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