产品说明
应用
24(R/S),25-epoxycholesterol has been used as liver X receptor ligand in breast cancer cell lines.
生化/生理作用
24(R/S),25-epoxycholesterol (24(R/S),25-EC) is a side chain substituted cholesterol. It is an effective activator of liver X receptor (LXR) transcription. 24R and 24S epimers of epoxycholesterol inhibit cholesterol synthesis from 24,25-dihydrolanosterol. The levels of 24(R/S),25-EC is elevated in gastric carcinoma and may also inhibit gastric tumor invasion. 24(R/S),25-EC regulates gastric epithelial function and also may modulates the phosphatidylinositol 3-kinase - protein kinase B (PI3K/AKT) signaling.
包装
5 mL Amber Glass Screw Cap Vial (700037P-1mg)
基本信息
经验(实验)分子式 | C27H44O2 |
分子量 | 400.64 |
NACRES | NA.25 |
产品性质
形式 | powder |
包装 | pkg of 1 × 1 mg (700037P-1mg) |
manufacturer/tradename | Avanti Polar Lipids 700037P |
运输 | dry ice |
储存温度 | −20℃ |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
Sigma-Aldrich