产品说明
一般描述
7α-Hydroxy-3-oxo-4-cholestenoic acid (7-HOCA) is synthesized extrahepatically from cholesterol. The enzyme oxysterols-7α-hydrolase (CYP7B1) acts on precursor 27-hydroxycholesterol (27-OHC) to generate 7-HOCA.. 7-HOCA is catabolized in the liver.
应用
7α-hydroxy-3-oxo-4-cholestenoic acid has been used as an analyte in ultra-high-performance liquid chromatography (UHPLC) system.
生化/生理作用
The levels of 7α-hydroxy-3-oxo-4-cholestenoic acid (7-HOCA) in cerebrospinal fluid are not correlated to neurodegeneration but may serve as a diagnostic marker to trace blood-brain barrier integrity.
包装
5 mL Amber Glass Screw Cap Vial (700027P-1mg)
基本信息
经验(实验)分子式 | C27H42O4 |
分子量 | 430.62 |
NACRES | NA.25 |
产品性质
测定 | >99% (TLC) |
形式 | powder |
包装 | pkg of 1 × 1 mg (700027P-1mg) |
manufacturer/tradename | Avanti Polar Lipids 700027P |
运输 | dry ice |
储存温度 | −20℃ |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
Sigma-Aldrich