产品说明
一般描述
7α,27-dihydroxycholesterol (7α,27-di-OHC) is an oxysterol with oxidized side chains. 7α,27-dihydroxycholesterol (7α27-OHC) is synthesized by the hydroxylation of 27-Hydroxycholesterol (27-OHC) and is a structural isomer of 7α,25-dihydroxycholesterol (7α25-OHC).
生化/生理作用
7α,27-dihydroxycholesterol (7α,27-di-OHC) is one of the metabolite screened in pathological conditions such as neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome and diabetes by lipidomics analysis of human specimens. Upon the lipopolysaccharide activation, the levels of 7α,27-di-OHC decreases.7α27-OHC is a ligand for Epstein-Barr virus-induced gene 2 (EBI2).
包装
5 mL Amber Glass Screw Cap Vial (700024P-1mg)
基本信息
经验(实验)分子式 | C27H46O3 |
分子量 | 418.65 |
NACRES | NA.25 |
产品性质
形式 | powder |
包装 | pkg of 1 × 1 mg (700024P-1mg) |
manufacturer/tradename | Avanti Polar Lipids 700024P |
运输 | dry ice |
储存温度 | −20℃ |
InChI | 1S/C27H46O3/c1-17(16-28)6-5-7-18(2)21-8-9-22-25-23(11-13-27(21,22)4)26(3)12-10-20(29)14-19(26)15-24(25)30/h15,17-18,20-25,28-30H,5-14,16H2,1-4H3/t17?,18-,20+,21-,22+,23+,24-,25+,26+,27-/m1/s1 |
InChI key | RXMHNAKZMGJANZ-DTTSCKGMSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
Sigma-Aldrich