产品说明
一般描述
8(9)-dehydrocholesterol is an isomer of 7-dehydrocholesterol and non-polar oxysterol metabolite. It is oxidized to Δ8 analog by mitochondrial enzymes.
应用
8(9)-dehydrocholesterol has been used as a component of sterol standard in liquid chromatography–mass spectrometry (LC-MS) for quantification of lipids from cultured cells.
生化/生理作用
8(9)-dehydrocholesterol (8-DHC) elevated levels are toxic to cells and is implicated in Smith-Lemli-Opitz syndrome (SLOS). 8-DHC profiling helps in understanding SLOS phenotype.
包装
5 mL Amber Glass Screw Cap Vial (700075P-1mg)
基本信息
| 经验(实验)分子式 | C27H44O |
| 分子量 | 384.64 |
| NACRES | NA.25 |
产品性质
| 测定 | >99% (TLC) |
| 形式 | powder |
| 包装 | pkg of 1 × 1 mg (700075P-1mg) |
| manufacturer/tradename | Avanti Polar Lipids 700075P |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| SMILES string | C[C@]1(CC2)C(CCC1C(CCCC(C)C)C)C3=C2[C@](CC[C@H](O)C4)(C)C4=CC3 |
| InChI | 1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21,23-24,28H,6-8,10-17H2,1-5H3/t19-,21+,23-,24+,26+,27-/m1/s1 |
| InChI key | VUKORTMHZDZZFR-BXAZICILSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
Sigma-Aldrich
m.cnreagent.com
