Acetyl-Amyloid β-Protein Fragment 15-20 Amide

产品名称：

189064-06-0
Acetyl-Amyloid β-Protein Fragment 15-20 Amide
Ac-QKLVFF-NH₂
amyloid blocker

产品介绍：

产品说明

Amino Acid Sequence

Ac-Gln-Lys-Leu-Val-Phe-Phe-NH2

包装

1 mg in glass bottle

生化/生理作用

Amyloid plaques characteristic of the Alzheimer brain contain fibrils composed of amyloid beta aggregates. Short peptides containing the sequence KLVFF have been shown to bind specifically to the homologous region in Aβ and are used to prevent full length amyloid fibril formation.

基本信息

经验(实验)分子式	C₄₂H₆₃N₉O₈
分子量	822.01
MDL编号	MFCD17215285
PubChem化学物质编号	329770908
NACRES	NA.32

产品性质

质量水平	200
测定	≥97% (HPLC)
形式	powder
颜色	white
UniProt登记号	P05067
储存温度	−20℃
SMILES string	CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc2ccccc2)C(N)=O
InChI	1S/C42H63N9O8/c1-25(2)22-33(49-38(55)30(18-12-13-21-43)47-39(56)31(46-27(5)52)19-20-35(44)53)41(58)51-36(26(3)4)42(59)50-34(24-29-16-10-7-11-17-29)40(57)48-32(37(45)54)23-28-14-8-6-9-15-28/h6-11,14-17,25-26,30-34,36H,12-13,18-24,43H2,1-5H3,(H2,44,53)(H2,45,54)(H,46,52)(H,47,56)(H,48,57)(H,49,55)(H,50,59)(H,51,58)/t30-,31-,32-,33-,34-,36-/m0/s1
InChI key	DDXTVYDSGCHGAN-PITCCTKHSA-N
Gene Information	human ... APP(351)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)