Biphalin trifluoroacetate salt

产品名称：

126872-95-5
Biphalin trifluoroacetate salt
L-Tyrosyl-D-alanylglycyl-L-phenylalanine 2-(L-tyrosyl-D-alanylglycyl-L-phenylalanyl)hydrazide
1,2-Bis(L-Tyr-D-Ala-Gly-L-Phe-)hydrazine

产品介绍：

产品说明

Amino Acid Sequence

(Tyr-DAla-Gly-Phe-NH)2

包装

1 mg in glass bottle

生化/生理作用

Biphalin is a dimeric enkephalin that is a potent and non-selective opioid receptors (OR) agonist. It displays a high analgesic potency that is over 1000-fold greater than morphine. Studies show that biphalin exhibits neuroprotective effects in rat models of stroke.
Biphalin trifluoroacetate salt, a highly active synthetic octapeptide, is an analog of biphalin. It displays a strong affinity in the nanomolar range for the receptors μ and δ.

特点和优势

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₄₆H₅₆N₁₀O₁₀ · xC₂HF₃O₂
分子量	909.00 (free base basis)
MDL编号	MFCD23380198
PubChem化学物质编号	329825305
NACRES	NA.77

产品性质

质量水平	100
测定	≥97% (HPLC)
形式	lyophilized solid
颜色	white to beige
运输	wet ice
储存温度	−20℃
SMILES string	OC(=O)C(F)(F)F.C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)NNC(=O)[C@H](Cc3ccccc3)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc4ccc(O)cc4
InChI	1S/C46H56N10O10.C2HF3O2/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32;3-2(4,5)1(6)7/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66);(H,6,7)/t27-,28-,35+,36+,37+,38+;/m1./s1
InChI key	KNKVMVJCRGCBFW-GJLSYRFBSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable