产品说明
一般描述
胆固醇逆向转运 (RCT) 是通过转运至肝脏及其粪便排泄，降低外周脂质负荷的机制。RCT 的第一步是动脉粥样硬化斑块中巨噬细胞源性泡沫细胞的胆固醇流出。胆固醇外流对于维持动脉壁净胆固醇平衡和减少由富含脂质的巨噬细胞触发的促炎症反应至关重要。
应用
胆固醇外流测定试剂盒已用于胆固醇外流测定。
特点和优势
Compatible with high-throughput handling systems.
适用性
适用于细胞内胆固醇外流的测定。
原理
The Cholesterol Efflux Assay Kit is a high-throughput screening assay that measures cholesterol efflux in cells using fluorescent-labeled cholesterol (λEx = 482 nm/ λEm = 515 nm). It is suitable for serum, isolated, or recombinant lipoprotein samples. It may also be used to screen small molecules for their effect on cholesterol efflux and therefore, may be a valuable tool in drug discovery programs.
产品性质
| detection method | fluorometric |
| 储存温度 | −20℃ |
组份列表
组份不可单独销售
| 货号 | 组份 |
| Labeling Reagent | |
| Equilibration Buffer | |
| Reagent A | |
| Reagent B | |
| Cell Lysis Buffer | |
| Positive Control | |
| Serum Treatment Reagent |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | 188.6 °F - closed cup |
| 闪点(C) | 87 ℃ - closed cup |
Sigma-Aldrich
m.cnreagent.com
