Cholesterol Uptake Assay Kit

产品说明

一般描述

Cholesterol is a sterol and lipid present in cell membranes, and is transported in the bloodstream of all animals. It is used to form cell membranes and hormones, and plays important roles in cell signaling processes. Cellular regulation of cholesterol levels is a complex system in which irregularities have been tied to obesity and heart disease. Increased cholesterol uptake has also been linked to highly proliferative cancer cells. Through monitoring cellular cholesterol uptake, one can explore these growing health problems and screen for possible drug treatments.

特点和优势

Compatible with high-throughput handling systems.

适用性

Suitable for testing cholesterol uptake by adherent cells, screening of
cholesterol uptake inhibitors, and evaluation of effect of drugs on
cholesterol uptake.

原理

The cholesterol uptake assay kit is based on cellular uptake of a fluorescently tagged cholesterol probe. The fluorescence intensity measured at λex/em = 485/535 nm is proportional to the amount of cholesterol uptaken by the cells.

产品性质

安全信息

象形图
警示用语：	Danger
危险声明	H225 - H319 - H336 - H371
预防措施声明	P210 - P233 - P240 - P241 - P305 + P351 + P338 - P308 + P311
危险分类	Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 2 - STOT SE 3
靶器官	Central nervous system, Eyes
储存分类代码	3 - Flammable liquids