松香酸-8,11,13-三烯-18-酸

产品名称：

1740-19-8
Dehydroabietic acid
Abieta-8,11,13-trien-18-oic acid
Dehydroabietate
脱氢枞酸
脱氢碳酸酯
松香酸-8,11,13-三烯-18-酸

产品介绍：

产品说明

一般描述

脱氢枞酸(DHA 或 DAA)是一种具有生物活性的双萜类植物化学物质，存在于各种松属物种中。它是树脂酸和松香酸(AA)的衍生物。

应用

Dehydroabietic acid has been used as a reference standard:

to study the aging process of Pinus resins using Fourier-transform infrared spectroscopy (FTIR)
to study the composition changes in Pinus genus with aging using Raman spectroscopy complemented with infrared spectroscopy
to estimate resistance against biotic stress as proxy in chemical defenses in Pinus halepensis

生化/生理作用

Dehydroabietic acid (DHA) exerts various biological activities such as anti-cancer, anti-aging, antimicrobial, antiulcer, gastroprotective, and cytotoxic activities. It is a potent anti-inflammatory agent and a dual activator of peroxisome proliferator-activated receptors alpha and gamma (PPAR α/γ). DHA has an anti-aging effect and a sirtuin 1 (SIRT1) activating compound. It has antibacterial properties against multidrug-resistant strains. dehydroabietic acid and its derivatives have gastroprotective and cytotoxic effects.

基本信息

经验(实验)分子式	C₂₀H₂₈O₂
分子量	300.44
EC 号	217-102-8
MDL编号	MFCD09839012
PubChem化学物质编号	329824767
NACRES	NA.25

产品性质

测定	≥95% (LC/MS-ELSD)
形式	solid
储存温度	−20℃
SMILES string	CC(C)c1ccc2c(CC[C@H]3[C@@](C)(CCC[C@]23C)C(O)=O)c1
InChI	1S/C20H28O2/c1-13(2)14-6-8-16-15(12-14)7-9-17-19(16,3)10-5-11-20(17,4)18(21)22/h6,8,12-13,17H,5,7,9-11H2,1-4H3,(H,21,22)/t17-,19-,20-/m1/s1
InChI key	NFWKVWVWBFBAOV-MISYRCLQSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H410
预防措施声明	P273 - P301 + P310 + P330
危险分类	Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable