产品说明
一般描述
The Equine IL-1ra (interleukin 1 receptor antagonist) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of equine IL-1ra in serum, plasma, cell culture supernatants and urine.
免疫原
Recombinant Equine IL-1 Receptor Antagonist
应用
请参考Protocol了解详情。
生化/生理作用
Interleukin-1 receptor antagonist (IL-1RA) inhibits the activity of IL-1α and IL-1β by competitively binding to their type I and type II receptors. IL-1RA plays a vital role in inhibition of acute pro-inflammatory response and forbidding chronic inflammation from damaging healthy tissues. Abnormal expression of IL-1RA leads to development of inflammatory or autoimmune related diseases. Allelic polymorphism of IL-1Rα leads to inflammatory bowel disease (IBD). Therapeutically, IL-1Rα may help in the treatment of sepsis, rheumatoid arthritis, asthma. Overexpression of IL-1Rα is observed in serum of psoriatic arthritis (PsA) patients.
其他说明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
基本信息
NACRES | NA.32 |
产品性质
质量水平 | 100 |
species reactivity | equine |
包装 | kit of 96 wells (12 strips x 8 wells) |
technique(s) | ELISA: suitable capture ELISA: suitable |
input | sample type serum sample type cell culture supernatant(s) sample type plasma |
assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 10 pg/mL standard curve range: 12.29-3000 pg/mL |
detection method | colorimetric |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | equine ... IL1RN(100034236) |
组份列表
组份可单独销售
货号 | 组份 |
RABELADB | ELISA 5X Assay/Sample Diluent Buffer B (Item E1) |
RABELADC | ELISA 1X Assay/Sample Diluent Buffer C (Item L) |
RABSTOP3 | ELISA Stop Solution (Item I) |
RABTMB3 | ELISA Colorimetric TMB Reagent (HRP Substrate, Item H) |
RABWASH4 | 20X Wash Buffer (Item B) |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H290 |
预防措施声明 | P234 - P390 |
危险分类 | Met. Corr. 1 |
储存分类代码 | 8A - Combustible, corrosive hazardous materials |
WGK | WGK 3 |
Sigma-Aldrich