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Histone H2a full length human

组蛋白 H2a 全长,人

品牌
Sigma-Aldrich
货号
SRP0406
规格纯度
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
参考价格
9148.9 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Histone H2a full length human
H2AFQ
histone cluster 2, H2ac
组蛋白 H2a 全长,人
产品介绍:

产品说明

一般描述

Histones make up the nucleosome, which is the fundamental unit of the chromatin. Each nucleosome consists of 146 base pairs of DNA which is wrapped around an octamer of four core histones H2A, H2B, H3 and H4. Histone cluster 2 H2A family member c (HIST2H2AC) has many variants. Human Histone 2A (GenBank Accession No. NM_033445) amino acids 2-130 (end) with N-terminal His-tag, MW = 14.8 kDa, expressed in an E. coli expression system.
Histone cluster 2 H2A family member c (HIST2H2AC) is located on human chromosome 1q21. It is usually present in undifferentiated/proliferating cells. This canonical histone isoform has a protruding tail at both the N- and C-termini.

生化/生理作用

Histone cluster 2 H2A family member c (HIST2H2AC) has a role in maintaining the structure of the chromatin.
Histone cluster 2 H2A family member c (HIST2H2AC) participates in multiple epigenetic regulations and carcinogenesis. It also participates in embryonic stem (ES) cell biology and regulates the expression of genes. It modulates proliferation and epithelial-mesenchymal transition in mammary epithelial and breast cancer cells. Hist2h2ac also controls epithelial differentiation.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in E. coli
测定≥90% (SDS-PAGE)
形式aqueous solution
分子量 14.8 kDa
包装pkg of 1 mg
储存条件avoid repeated freeze/thaw cycles
浓度1.2 mg/mL
NCBI登记号NM_033445
UniProt登记号Q16777
运输dry ice
储存温度−70℃
Gene Informationhuman ... HIST2H2AC(8338)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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