产品说明
一般描述
Phosphatidic acid (PA) is a simple anionic membrane phospholipid. The phospholipid contains phosphomonoester polar head group and two long hydrophobic acyl chains. 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) PA is a fluorescent analog with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) attached to the sn-2 fatty acid of PA.
应用
16:0-06:0 NBD PA 1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphate is suitable to measure the substrate transport by an increase in cellular fluorescence to determine type 4 P-type ATPases (P4-ATPase) discrimination and its glycerophospholipid (GPL) substrate selection through the directed evolution of a sphingomyelin (SM) flippase.
生化/生理作用
Phosphatidic acid (PA) is crucial for intracellular signaling involved various cellular processes including membrane trafficking and sperm hyper-activation. It plays a vital role in lipid synthesis.
包装
5 mL Amber Glass Screw Cap Vial (810173P-1mg)
基本信息
| 经验(实验)分子式 | C31H54N5O11P |
| 分子量 | 703.76 |
产品性质
| 测定 | >99% (TLC) |
| 形式 | powder |
| 包装 | pkg of 1 × 1 mg (810173P-1mg) |
| manufacturer/tradename | Avanti Polar Lipids 810173P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
Sigma-Aldrich
m.cnreagent.com
