产品说明
一般描述
4E,14Z-Sphingadiene is a unique sphingoid base containing C18 chain, with trans double bond at C-4 and cis double bond between C14 and C15 with a bent structure. It is found in the plasma, lymph, brain, kidney and lungs of humans and mice. 4E,14Z-Sphingadiene or d-erythro-1,3-dihydroxy-2-amino-4-trans-14-cis-octadecadiene is the second largest long-chain base of human plasma sphingomyelins.
生化/生理作用
Sphingadiene, a vital component of sphingolipids facilitates numerous processes such as apoptosis and cell signaling. It inhibits Akt/Wnt signaling and acts as an anticancer agent in colon cancer.
包装
5 mL Amber Glass Screw Cap Vial (860665P-1mg)
基本信息
经验(实验)分子式 | C18H35NO2 |
分子量 | 297.48 |
NACRES | NA.25 |
产品性质
形式 | powder |
包装 | pkg of 1 × 1 mg (860665P-1mg) |
manufacturer/tradename | Avanti Polar Lipids 860665P |
运输 | dry ice |
储存温度 | −20℃ |
SMILES string | OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCC/C=C\CCC |
InChI | 1S/C18H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h4-5,14-15,17-18,20-21H,2-3,6-13,16,19H2,1H3/b5-4-,15-14+ |
InChI key | KWDXKYNWAKMLKK-YQMRQDNGSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
Sigma-Aldrich