产品说明
一般描述
7-dehydrodesmosterol (7-DHD) is synthesized via the Bloch pathway. 7-DHD serves as a desmosterol synthesis precursor and the enzyme 7-dehydrocholesterol reductase (DHCR7) catalyzes this step.
应用
7-dehydrodesmosterol has been used as an internal oxysterol standard in ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).
生化/生理作用
7-dehydrodesmosterol (7-DHD) levels are higher during fetal development and increases with aging. Elevated levels of 7-DHD is associated with Smith-Lemli-Opitz syndrome mouse model. Reduced levels of 7-DHD is observed in shiverer and quaking disorder.
包装
5 mL Amber Glass Screw Cap Vial (700138P-1mg)
基本信息
经验(实验)分子式 | C27H42O |
分子量 | 382.62 |
NACRES | NA.25 |
产品性质
形式 | powder |
包装 | pkg of 1 × 1 mg (700138P-1mg) |
manufacturer/tradename | Avanti Polar Lipids 700138P |
运输 | dry ice |
储存温度 | −70℃ |
InChI | 1S/C27H42O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9-10,19,21,23-25,28H,6,8,11-17H2,1-5H3/t19-,21+,23-,24+,25+,26+,27-/m1/s1 |
InChI key | RUSSPKPUXDSHNC-DDPQNLDTSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
Sigma-Aldrich