产品说明
一般描述
7α,27-dihydroxy-4-cholesten-3-one synthesized by the hydroxylation of 27-hydroxycholesterol in the presence of the enzyme cholesterol 7 α-hydroxylase (CYP7A1) and is catabolized to bile acid. 7α,27-dihydroxy-4-cholesten-3-one is present majorly in fibroblasts and its conversion from cholesterol occurs in extrahepatic tissues.
应用
7α,27-dihydroxy-4-cholesten-3-one may be used as a ligand to test its effect on Epstein-Barr virus-induced molecule 2 (EB12) activation in guanosine 5′-O-(3-thio)triphosphate ([35S] GTPγS) binding assay.
生化/生理作用
7α,27-dihydroxy-4-cholesten-3-one is a suppressor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase.
包装
5 mL Amber Glass Screw Cap Vial (700023P-1mg)
基本信息
| 经验(实验)分子式 | C27H44O3 |
| 分子量 | 416.64 |
产品性质
| 形式 | powder |
| 包装 | pkg of 1 × 1 mg (700023P-1mg) |
| manufacturer/tradename | Avanti Polar Lipids 700023P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
Sigma-Aldrich
m.cnreagent.com
