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AC253 trifluoroacetate salt

品牌
Sigma-Aldrich
货号
SML0625
包装型号
规格纯度
≥95% (HPLC)
参考价格
4383.32 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
AC253 trifluoroacetate salt
Amylin Antagonist AC253
产品介绍:

产品说明

Amino Acid Sequence

Ac-Leu-Gly-Arg-Leu-Ser-Gln-Glu-Leu-His-Arg-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2

包装

1 mg in glass bottle

生化/生理作用

AC253 is an antagonist of Amylin, one of the peptides in the Calcitonin-gene related peptide (CGRP) family. In recent studies. AC253 restored memories in brain cells taken from animals used as models of Alzheimer′s disease. Application of AC253 significantly enhanced long-term potentiation (LTP) when given to 6- to 12-month-old TgCRND8 mice that normally show blunted LTP. In other studies, AC25 neutralized the depressant effects of Aβ(1-42) on hippocampal LTP without affecting baseline transmission or LTP on its own.

特点和优势

This compound is featured on the Calcitonin Gene-Related Peptides page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C122H196N40O39 · xC2HF3O2
分子量2847.11 (free base basis)
NACRESNA.77

产品性质

质量水平100
测定≥95% (HPLC)
形式powder
颜色 white to off-white
运输wet ice
储存温度−20℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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