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ACE1 Inhibitor Screening Kit (Colorimetric)

品牌
Sigma-Aldrich
货号
MAK422
规格纯度
sufficient for 100 colorimetric tests
参考价格
11520.6 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
ACE1 Inhibitor Screening Kit (Colorimetric)
产品介绍:

产品说明

一般描述

Angiotensin-I-converting enzyme (ACE) is a peptidyl dipeptidase that catalyzes the conversion of decapeptide angiotensin I to octapeptide angiotensin II, by removing a carboxy-terminal dipeptide. ACE is a key part of the renin angiotensin system that regulates blood pressure. ACE inhibitor inhibits ACE1 enzymatic activity and decreases the production of angiotensin II. As a result, blood vessels are dilated thereby increasing the amount of blood pumped by the heart and lowering the blood pressure. ACE inhibitors are used for treating hypertension, heart failure, stroke etc. Recent research is also focused on the discovery of natural products as ACE1 Inhibitors.

特点和优势

ACE1 Inhibitor Screening Kit:

  • Compatible with high-throughput handling systems.

适用性

The kit is suitable for the screening/characterizing of ACE1 inhibitors.

原理

The ACE1 Inhibitor Screening Kit can be used to screen potential ACE1 inhibitors. The kit utilizes the ability of an active ACE1 to hydrolyze a synthetic substrate, which results in the decrease in A345 nm. In the presence of Captopril, an ACE1 specific inhibitor, the ACE1 enzymatic activity is greatly reduced and there is no significant decrease in the A345 nm. The assay kit provides a rapid, simple and reliable test for high-throughput screening of ACE1 inhibitors.

产品性质

质量水平100
web metadata keyword.defaultACE1 Inhibitor Screening Kit (Colorimetric)|sigma-aldrich
detection methodcolorimetric
储存温度−20℃

安全信息

象形图GHS08
警示用语:Danger
危险声明H360F
预防措施声明P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类Repr. 1B
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Sigma-Aldrich

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