产品说明
生化/生理作用
Andrastin A is a meroterpenoid protein farnesyltransferase inhibitor with anticancer activity. It has been shown to inhibit the farnesyltransferase activity of the oncogenic Ras proteins and inhibit the efflux of anticancer drugs from multidrug-resistant cancer cells.
Farnesyltransferase inhibitor with anticancer activity; mycotoxin
基本信息
经验(实验)分子式 | C28H38O7 |
分子量 | 486.60 |
MDL编号 | MFCD28898503 |
产品性质
测定 | ≥95% (HPLC) |
形式 | powder |
颜色 | white to beige |
储存温度 | −20℃ |
InChI | 1S/C28H38O7/c1-15-13-19-25(6,28(23(33)34-8)22(32)16(2)21(31)26(15,28)7)11-9-18-24(4,5)20(35-17(3)30)10-12-27(18,19)14-29/h13-14,16,18-20H,9-12H2,1-8H3/t16?,18?,19-,20?,25?,26+,27+,28?/m0/s1 |
InChI key | GRBXNADBNJGZRK-BCMOVVIDSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich