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Cathepsin D Assay Kit

品牌
Sigma-Aldrich
货号
MAK383
规格纯度
sufficient for 100 fluorometric tests
参考价格
6019.62 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Cathepsin D Assay Kit
产品介绍:

产品说明

一般描述

Apoptosis can be mediated by mechanisms other than the traditional caspase-mediated cleavage cascade. There is growing recognition that alternative proteolytic enzymes such as the lysosomal cathepsin proteases may initiate or propagate proapoptotic signals. Cathepsins are lysosomal enzymes that are also used as sensitive markers in various toxicological investigations.

特点和优势

The Cathepsin-D Activity Assay kit:

  • Is a simple one-step procedure with results in 1-2 hours.

适用性

The kit is suitable for the detection of Cathepsin-D activity in cell lysates.

原理

The Cathepsin-D Activity Assay kit is a fluorescence-based assay that utilizes the preferred cathepsin-D substrate sequence GKPILFFRLK(Dnp)-DR-NH2) labeled with 7-Methoxycoumarin-4-acetic acid (MCA). Cell lysates or other samples that contain cathepsin-D will cleave the synthetic substrate to release fluorescence, which can then easily be quantified fluorometrically at λEx = 328 nm/λEm = 460nm.

产品性质

质量水平100
web metadata keyword.defaultCathepsin D Assay Kit|sigma-aldrich
detection methodfluorometric
储存温度−20℃

安全信息

储存分类代码10 - Combustible liquids

Sigma-Aldrich

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