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Cyclotraxin-B trifluoroacetate salt

品牌
Sigma-Aldrich
CAS
1203586-72-4
货号
SML1769
包装型号
规格纯度
≥95% (HPLC)
参考价格
3349.38 *本价格含增值税费
促销
服务
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数量
-+
产品名称:
1203586-72-4
Cyclotraxin-B trifluoroacetate salt
L-Cysteinyl-L-asparaginyl-L-prolyl-L-methionylglycyl-L-tyrosyl-L-threonyl-L-lysyl-L-a-glutamylglycyl-L-cysteine, cyclic (1>11)-disulfide
CNPMGYTKEGC (Modifications: Disulfide bridge between 1-11)
产品介绍:

产品说明

包装

1 mg in glass bottle

生化/生理作用

Cyclotraxin-B is a potent and selective Trk B (BDNF/NT-3) receptor inhibitor. Cyclotraxin-B prevents receptor activation by BDNF without interfering with BDNF binding. Cyclotraxin-B has an IC50 value < 1 nM. In rodent studies Cyclotraxin-B, sometimes fused with tat-protein for increased brain permeability, has been shown to have anxiolytic properties, prevent cold hypersensitivity induced by BDNF, and to reduce cocaine self-administration.

基本信息

经验(实验)分子式C48H73N13O17S3 · xC2HF3O2
分子量1200.37 (free base basis)

产品性质

质量水平100
测定≥95% (HPLC)
形式film
颜色 colorless
运输wet ice
储存温度−20℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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